Sequential production of secondary metabolites by one operon affects interspecies interactions in Enterobacter sp. CGMCC 5087

Lijuan Liu, Guoqiang Chen, Jianhui Liu, Wenzhi Bao, Xing Li, Kaiguang Yang, Sujuan Shi, Baofeng Zhao, Qian Wang, Xiaohe Cao, Jiming Wang, Xiao Men, Fan Wang, Ge Zhang, Lihua Zhang*, Haibo Zhang*

The Innovation Life, 2023,1(2),100023.

（链接：https://doi.org/10.59717/j.xinn-life.2023.100023）

In Situ Fermentation of an Ultra-Strong, Microplastic-Free, and Biodegradable Multilayer Bacterial Cellulose Film for Food Packaging

Yibing Zhang, Guoqiang Chen, Wenhao Qin, Xiao Men, Lijuan Liu, Yashu Zhang, Qingtao Li*, Lei Wang*, Haibo Zhang*

ACS Applied Materials & Interfaces, 2023,15,37,44354-44363.

（链接：https://pubs.acs.org/doi/full/10.1021/acsami.3c10563）

A pH-stable alkaline pectate lyase produced by the newly identified strain Bacillus altitudinis CAS-WZS-08

Ge Zhang, Fan Wang,Shuaijun Deng, Guoqiang Chen, Haobao  Liu*, Haibo Zhang*

Journal of King Saud University Science, 2023,35(4),102649.

（链接：https://doi.org/10.1016/j.jksus.2023.102649）

A Single Active-Site Mutagenesis Confers Enhanced Activity and/or Changed Product Distribution to a Pentalenene Synthase from Streptomyces sp. PSKA01

Hongshuang Liu, Senbiao Fang, Lin Zhao*, Xiao Men*, Haibo Zhang*

Bioengineering, 2023, 10, 392.

（链接：https://doi.org/10.3390/bioengineering10030392）

Extraction, characterization, and biological activities of exopolysaccharides from plant root soil fungus Fusarium merismoides A6

Guoqiang Chen, Zhenxiang Xu, Fan Wang, Lijuan Liu, Yuxi Wei, Jinglong Li, Liang Zhang, Kai Zheng*, Lijun Wu*, Xiao Men*, Haibo Zhang

Brazilian Journal of Microbiology，2022.

（链接：https://doi.org/10.1007/s42770-022-00842-x）

Engineering for life in toxicity: key to industrializing microbial synthesis of high energy density fuels

Lijuan Liu, Wenzhi Bao, Xiao Men, Haibo Zhang*

Engineering Microbiology,2022: 100013.

（链接：https://doi.org/10.1016/j.engmic.2022.100013）

The characterization of an efficient phenylpyruvate decarboxylase KDC4427, involved in 2-Phenylethanol and IAA production from bacterial Enterobacter sp. CGMCC 5087

Wenzhi Bao, Xing Li, Jinfeng Liu, Rong Zheng, Lijuan Liu*, Haibo Zhang*

Microbiology Spectrum, 2022.

（链接：https://doi.org/10.1128/spectrum.02660-21）

The diversity, structure and function of microbial communities changes across aging process of tobacco leaves

Fan Wang, Yongming Jin, Xiaona Chen, Yao Zhang, Xinglin Jiang, Ge Zhang, Guoqiang Chen, Mingjun Yang, Feifan Leng, Hongtao Li*, Lijun Wu*, Haibo Zhang*

Environmental Research Communications，2022.

（链接：https://doi.org/10.1088/2515-7620/ac9352）

Structural characterization, antioxidant and antitumor activities of the two novel exopolysaccharides produced by Debaryomyces hansenii DH-1

Yajing Yang, Guoqiang Chen, Xiaoqi Zhao, Xiaohe Cao, Lei Wang, Jingjiu Mu, Fenghui Qi*, Lijuan Liu*, Haibo Zhang

International Journal of Molecular Sciences, 2022.

（链接: https://doi.org/10.3390/ijms24010335）

Extraction, characterization, antioxidant activity and rheological behavior of a polysaccharide produced by the extremely salt tolerant Bacillus subtilis LR-1

Xiaoqi Zhao, Guoqiang Chen, Fan Wang, Han Zhao, Yuxi Wei*, Lijuan Liu*, Haibo Zhang

LWT-Food Science and Technology, 2022: 113413.

（链接：https://doi.org/10.1016/j.lwt.2022.113413）

Bitter and astringent substances in green tea: composition, human perception mechanisms, evaluation methods and factors influencing their formation

Shuaijun Deng, Ge Zhang, Oluwaseun Olayemi Alukoab, Zhijie Mo, Jingjing Mao, Haibo Zhang, Xiaohui Liu, Ming Ma, Qian Wang*, Haobao Liu*

Food Research International，2022：111262.

（链接：https://doi.org/10.1016/j.foodres.2022.111262）

Externally Supplied Mannitol and Trehalose Boost Phloroglucinol Biosynthesis in Escherichia coli

Fei Li, Tongqing Yue, Jiming Wang*, Haibo Zhang*

Applied Biochemistry and Microbiology，2022.

（链接：https://link.springer.com/article/10.1134/S0003683822040093）

Insights into the Structures, Inhibitors, and Improvement Strategies of Glucose Oxidase

Fan Wang, Xiaona Chen, Yonggang Wang, Xing Li, Minglai Wan, Ge Zhang, Feifan Leng, Haibo Zhang*

International Journal of Molecular Sciences，2022, 23(17), 9841.

（链接：https://doi.org/10.3390/ijms23179841）

Common problems associated with the microbial productions of aromatic compounds and corresponding metabolic engineering strategies

Meijie Li, Changqing Liu, Jianming Yang, Rui Nian, Mo Xian*, Fuli Li*, Haibo Zhang*

Biotechnology Advances, 2020: 107548.

（链接：https://doi.org/10.1016/j.biotechadv.2020.107548）

Recent advances of metabolic engineering strategies in natural isoprenoid production using cell factories

Meijie Li, Feifei Hou, Tong Wu, Xinglin Jiang, Fuli Li, Haobao Liu*, Mo Xian*, Haibo Zhang*

Natural Product Reports, 2020, 37(1): 80-99.

（链接：https://doi.org/10.1039/C9NP00016J）

Construction of arming Yarrowia lipolytica surface-displaying soybean seed coat peroxidase for use as whole-cell biocatalyst

Jiming Wang, Chaoming Wang, Xiao Men, Tongqin Yue, Catherine Madzak, Xiaohua Xiang, Haiying Xiang*, Haibo Zhang*

Enzyme and Microbial Technology, 2020, 135: 109498.

（链接：https://doi.org/10.1016/j.enzmictec.2019.109498）

Comparative study on pretreatment processes for different utilization purposes of switchgrass

Fan Wang, Dongxiang Shi, Ju Han, Ge Zhang, Xinglin Jiang, Mingjun Yang, Zhenying Wu, Chunxiang Fu, Zhihao Li, Mo Xian,  Haibo Zhang*

ACS Omega, 2020, 5(35): 21999-22007.

（链接：https://doi.org/10.1021/acsomega.0c01047）

Improvement of sabinene tolerance of Escherichia coli using adaptive laboratory evolution and omics technologies

Tong Wu, Jinfeng Liu, Meijie Li, Ge Zhang, Lijuan Liu, Xing li, Xiao Men*, Mo Xian*, Haibo Zhang*

Biotechnology for Biofuels, 2020, 13: 1-15.

（链接：https://doi.org/10.1186/s13068-020-01715-x）

Metabolic engineering of different microbial hosts for lycopene production

Meijie Li, Qingqing Xia, Haibo Zhang, Rubing Zhang, Jianming Yang*

Journal of Agricultural and Food Chemistry, 2020, 68(48):14104-14122.

（链接：https://doi.org/10.1021/acs.jafc.0c06020）

Automating cloning by natural transformation

Xinglin Jiang, Emilia Palazzotto, Ewa Wybraniec, Lachlan Jake Munro, Haibo Zhang, Douglas B. Kell, Tilmann Weber*, Sang Yup Lee*

ACS Synthetic Biology. 2020, 9, 12, 3228–3235.

（链接：https://doi.org/10.1021/acssynbio.0c00240）

甲羟戊酸途径的代谢支路调控策略的研究进展

徐镇祥， 李美洁， 门潇， 陈国强， 王纪明， 咸漠， 张海波*

生物加工过程, 2020, 18(1): 44-51.

（链接： https://doi.org/10.3969/j.issn.1672-3678.2020.01.006 ）

A natural in situ fabrication method of functional bacterial cellulose using a microorganism

Minghong Gao, Juan Li, Zixian Bao, Moudong Hu, Rui Nian, Dexin Feng, Dong An, Xing Li, Mo Xian*, Haibo Zhang*

Nature Communications, 2019, 10(1): 1-10.

（链接：https://doi.org/10.1038/s41467-018-07879-3）

Biochemical characterization of isoprene synthase from Ipomoea batatas

Meijie Li, Changqing Liu, Hailin Chen, Li Deng, Haibo Zhang, Rui Nian, Mo Xian*

Journal of Bioscience and Bioengineering, 2019, 127(2): 138-144.

（链接：https://doi.org/10.1016/j.jbiosc.2018.07.022）

Improvement of isoprene production in Escherichia coli by rational optimization of RBSs and key enzymes screening

Meijie Li, Hailin Chen, Changqing Liu, Jing Guo, Xin Xu, Haibo Zhang*, Rui Nian*, Mo Xian*

Microbial Cell Factories, 2019, 18(1): 1-12.

（链接：https://doi.org/10.1186/s12934-018-1051-3）

Biosynthesis of natural rubber: current state and perspectives

Xiao Men, Fan Wang, Guoqiang Chen, Haibo Zhang*, Mo Xian*

International Journal of Molecular Sciences, 2019, 20(1): 50.

（链接： https://doi.org/10.3390/ijms20010050 ）

烤烟烟叶淀粉含量5种测定方法的比较

王娟，王帆，张鸽，辛玉华，张海波，刘好宝*

分子植物育种, 2019 (5): 39.

（链接： https://doi.org/10.13271/j.mpb.017.001673 ）

Genome mining of 2-phenylethanol biosynthetic genes from Enterobacter sp. CGMCC 5087 and heterologous overproduction in Escherichia coli

Changqing Liu, Kai Zhang, Wenyan Cao, Ge Zhang, Guoqiang Chen, Haiyan Yang, Qian Wang, Haobao Liu, Mo Xian*, Haibo Zhang*

Biotechnology for Biofuels, 2018, 11(1): 305.

（链接：https://doi.org/10.1186/s13068-018-1297-3）

Metabolic engineering for the production of isoprene and isopentenol by Escherichia coli

Meijie Li, Rui Nian, Mo Xian*, Haibo Zhang*

Applied Microbiology and Biotechnology, 2018, 102(18): 7725-7738.

（链接：https://doi.org/10.1007/s00253-018-9200-5）

A systematic optimization of styrene biosynthesis in Escherichia coli BL21(DE3)

Changqing Liu, Xiao Men, Hailin Chen, Meijie Li, Zhaorui Ding, Guoqiang Chen, Fan Wang, Haobao Liu, Qian Wang, Youshuang Zhu, Haibo Zhang*, Mo Xian*

Biotechnology for Biofuels, 2018, 11(1): 14.

（链接：https://doi.org/10.1186/s13068-018-1017-z ）

Enhancement of the catalytic activity of Isopentenyl diphosphate isomerase (IDI) from Saccharomyces cerevisiae through random and site-directed mutagenesis

Hailin Chen, Meijie Li, Changqing Liu, Haibo Zhang*, Mo Xian*, Huizhou Liu*

Microbial Cell Factories, 2018, 17(1): 1-14.

（链接：https://doi.org/10.1186/s12934-018-0913-z）

Production of bacterial cellulose using polysaccharide fermentation wastewater as inexpensive nutrient sources

Hongwei Zhao, Jian Xia, Jiming Wang, Xiaofei Yan, Cong Wang, Tingzhou Lei, Mo Xian, Haibo Zhang*

Biotechnology & Biotechnological Equipment, 2018, 32(2): 350-356.

（链接：https://doi.org/10.1080/13102818.2017.1418673）

Species diversity and functional prediction of surface bacterial communities on aging flue-cured tobaccos

Fan Wang, Hongwei Zhao, Haiying Xiang, Lijun Wu, Xiao Men, Chang Qi, Guoqiang Chen, Haibo Zhang*, Yi Wang*, Mo Xian*

Current Microbiology, 2018, 75(10): 1306-1315.

（链接：https://doi.org/10.1007/s00284-018-1525-x）

Production of γ-terpinene by metabolically engineered Escherichia coli using glycerol as feedstock

Chang Qi, Hongwei Zhao, Wenyang Li, Xing Li, Haiying Xiang, Ge Zhang, Haobao Liu*, Qian Wang, Yi Wang, Mo Xian*, Haibo Zhang*

RSC Advances, 2018, 8(54): 30851-30859.

（链接：https://doi.org/10.1039/C8RA02076K ）

Assessment of 16S rRNA gene primers for studying bacterial community structure and function of aging flue-cured tobaccos

Fan Wang, Xiao Men, Ge Zhang, Kaichao Liang, Yuhua Xin, Juan Wang, Aijun Li, Haibo Zhang*, Haobao Liu*, Lijun Wu*

AMB Express, 2018, 8(1): 1-9.

（链接：https://doi.org/10.1186/s13568-018-0713-1）

Directed evolution of mevalonate kinase in Escherichia coli by random mutagenesis for improved lycopene

Hailin Chen, Changqing Liu,  Meijie Li,   Haibo Zhang*, Mo Xian*, Huizhou Liu*

RSC Advances, 2018, 8(27): 15021-15028.

（链接：https://doi.org/10.1039/C8RA01783B）

基于高通量测序和传统分离研究雪茄外包皮表面细菌多样性及演替

张鸽，梁开朝，辛玉华，王娟，李书贵，李爱军，王帆，张海波*，刘好宝*

应用与环境生物学报 , 2018, 24(4): 0783-0788.

（链接： https://doi.org/10.19675/j.cnki.1006-687x.2017.11014）

Expression and characterization of soybean seed coat peroxidase in Escherichia coli BL21(DE3)

Changqing Liu, Kai Zheng, Ying Xu, Lacmata Tamekou Stephen, Jiming Wang, Hongwei Zhao, Tongqing Yue, Rui Nian, Haibo Zhang*, Mo Xian*, Huizhou Liu*

Preparative Biochemistry and Biotechnology, 2017, 47(8): 768-775.

链接：https://doi.org/10.1080/10826068.2017.1342258

Pullulan production from synthetic medium by a new mutant of Aureobasidium pullulans

Guoqiang Chen, Jiming Wang, Yulong Su, Youshuang Zhu, Ge Zhang, Hongwei Zhao,Haobao Liu, Ying Yang, Rui Nian, Haibo Zhang*, Yuxi Wei*, Mo Xian*

Preparative Biochemistry and Biotechnology, 2017, 47(10): 963-969.

链接：https://doi.org/10.1080/10826068.2017.1350979

Calcium supplementation abates the inhibition effects of acetic acid on Saccharomyces cerevisiae

Hongwei Zhao, Jingyuan Li, Jiming Wang, Xin Xu, Mo Xian, Huizhou Liu, Haibo Zhang*

Applied Biochemistry and Biotechnology, 2017, 181(4): 1573-1589.

链接：https://doi.org/10.1007/s12010-016-2303-5

Microbial production of amino acid-modified spider dragline silk protein with intensively improved mechanical properties

Haibo Zhang, Fengli Zhou, Xinglin Jiang, Mingle Cao, Shilu Wang, Huibin Zou, Yujin Cao, Mo Xian*, Huizhou Liu*

Preparative Biochemistry and Biotechnology, 2016, 46(6): 552-558.

链接：https://doi.org/10.1080/10826068.2015.1084637

Non-mediated oxidation of non-phenol dye methyl red with purified laccase from Trametes hirsuta lg-9

Haibo Zhang, Youshuang Zhu,  Yinglong Zhang,  Feng Huang*

Journal of Pure and Applied Microbiology, 2014, 8(1): 11-19.

链接：https://www.cabdirect.org/cabdirect/abstract/20143166280

Microbial production of sabinene—a new terpene-based precursor of advanced biofuel

Haibo Zhang, Qiang Liu, Yujin Cao, Xinjun Feng, Yanning Zheng, Huibin Zou, Hui Liu, Jianming Yang*, Mo Xian*

Microbial Cell Factories, 2014, 13(1): 20.

链接：https://doi.org/10.1186/1475-2859-13-20

De-novo synthesis of 2-phenylethanol by Enterobacter sp. CGMCC 5087

Haibo Zhang, Mingle Cao, Xinglin Jiang, Huibin Zou, Cong Wang, Xin Xu, Mo Xian*

BMC biotechnology, 2014, 14(1): 30.

链接：https://doi.org/10.1186/1472-6750-14-30

一种泰乐菌素降解菌及其筛选方法与应用

发明人：张海波，王纪明，咸漠，门潇，刘丽娟，王帆，张鸽，陈国强

专利号：2020106801494

一种高产法尼烯的重组菌及其构建方法与应用

发明人：张海波，门潇，咸漠，刘晋锋

专利号：202010366859X

一种高产法尼烯的基因工程菌及其构建方法与应用

发明人：张海波，门潇，咸漠，刘晋锋

专利号： 2020103681170

一种雪茄茄芯烟叶的四段式发酵方法

发明人：张海波，刘好宝，咸漠，梁开朝，辛玉华，张鸽，王帆，陈国强，沈忠，王娟，向小华

专利号： 2019109683938

一种利用特基拉芽孢杆菌固态发酵烟草废弃物产碱性果胶酶的方法

发明人：张海波，张鸽，咸漠，王帆，陈国强，门潇，刘丽娟，王纪明，李兴，李志豪

专利号： 2019113806184

一种降低雪茄烟叶堆垛过程中烧堆风险的两段式发酵方法

发明人：刘好宝，张海波，梁开朝，张鸽，咸漠，辛玉华，沈忠，王娟，向小华，陈国强，王帆

专利号： 2019109710244

一种雪茄外包皮烟叶保湿的方法

发明人：刘好宝，张海波，张鸽，梁开朝，李方友，蔡斌，向小华，沈忠，王娟，李志豪，陈国强

专利号： 2019113700160

一种合成β-法尼烯的基因工程菌及其及其构建方法与应用

发明人：张海波，刘丽娟，咸漠，齐畅，曹小贺

专利号： 2018116337174

一种提高异戊二烯产量的基因工程菌及其构建方法与应用

发明人：张海波，咸漠，刘长青，门潇，李美洁

专利号：2018116020643

一种烟叶废弃物的处理方法及其应用

发明人：张海波、王帆、咸漠、石东祥、门潇、刘丽娟、张鸽、陈国强

专利号： 2018113536693

一种通过改变非限速酶的核糖体结合位点提高异戊二烯工程菌产量的方法

发明人：张海波、李美洁、咸漠、吴桐

专利号：2018109166513

一株特基拉芽孢杆菌CAS-MEI-2-33及其应用

发明人：张海波，咸漠，张鸽，王帆

专利号： 2017114197926

耐热β-淀粉酶-海藻糖合成酶融合酶、其表达基因以及分泌该融合酶的工程菌与应用

发明人：张海波，王纪明，咸漠，王帆，高玉新，刘会洲

专利号：2017105127835

一种利用宏基因组测序辅助筛选烟草发酵过程中微生物的方法

发明人：张海波，王帆，咸漠，赵宏伟，刘会洲

专利号： 2017104912240

一种具有γ-松油烯合成能力的基因工程菌及其构建方法与应用

发明人：张海波，赵宏伟，咸漠，齐畅

专利号：2017104839368

一种高效生产低分子普鲁兰多糖的诱变菌株及其应用

发明人：张海波，咸漠，陈国强，王纪明，赵宏伟，刘会洲，刘炜

专利号：201710426406X